Pyrimidine-1,2,3-Triazole Hybrid Glycosides: Click Based Synthesis and Biological aspects

Abstract

Application of click chemistry for the construction of hybrid structure incorporating 1,2,3-triazole nucleus was extensively studied as a powerful strategy for designing a variety of targeted structures. The currents review focused on the synthetic pathways of compounds possessing two important motifs: pyrimidine and 1,2,3-triazole systems and their derived sugar derivatives as glycoside analogues. The reported bioactivities of the formed hybrid products were highlighted.