Complexes of Co(II), Ni(II) and Cu(II) with 2-((2- methoxybenzylidene)amino) acetohydrazide hydrate: Preparation, Characterization and Antimicrobial activities

Abstract

In this study, one new Schiff base hydrazide derived from 2-Methoxy benzaldehyde,
glycine and hydrazine hydrate as a ligand and its transition metal complexes were synthesized.
The structures of these compounds were characterized by using elemental analysis, magnetic
susceptibility measurements, conductivity, molar ratio, electronic, infrared, and NMR spectra,
X-ray diffraction, and antioxidant analysis. The ligand was found to be a bidentate ligand
involving the imino nitrogen and the nitrogen of amine in all complexes, in addition to the
oxygen of the carbonyl group in NiΙΙ complex. The metal to ligand ratios were found to be 1:1
for all of the prepared complexes. The Co(II) and Ni(II) complexes have been found in a square
planar geometry, while the complex of Cu(II) has octahedral geometry. Complexes of Co(II)
and Ni(II) have electrolytic nature but the complex of Cu(II) was not. The ligand and its
complexes were screened for their antifungal and antibacterial activity. The results indicated
that these compounds exhibited good antifungal and antibacterial activities.