Novel (3 S ,3a S ,6a S )-2-acetyl- N -methylhexahydrofuro[3,4- d ][1,2]oxazole-3-carboxamide has been synthesized by oxidative cleavage in the presence of m-CPBA in good yield. The analysis of the 1D and 2D NMR spectra unambiguously confirms the stereochemistry of the synthesized product. Bioinformatic study were carried out for the synthesized compound using Swiss ADME program to get insight of its appropriate ADME properties and to avoid the failure of candidate drugs at the clinical stage. Results show that (3 S ,3a S ,6a S )-2-acetyl- N -methylhexahydrofuro[3,4- d ][1,2]oxazole-3-carboxamide was within the range set by Lipinski’s rule of five, displayed higher gastrointestinal absorption and inhibition of all CYP isoforms.

Gold nanoparticles (AuNPS) are highly promising organisms for solving a wide range of medical problems due to their special properties and low toxicity. The production of gold nanoparticles by biological method (green synthesis) is environmentally friendly and allows to reduce the amount of harmful chemicals and toxic products. This review is devoted to anticancer biomedical gold nanoparticle applications, and a variety of cancer types are mentioned, including lung, breast, cervical, liver, colorectal, and drug delivery mechanism targeting cancer cells. Other applications of these nanoparticles in vaccines, enzyme inhibition, vaccines, dentistry, and their work as metal sensors and others were also discussed.

In this study, one new Schiff base hydrazide derived from 2-Methoxy benzaldehyde, glycine and hydrazine hydrate as a ligand and its transition metal complexes were synthesized. The structures of these compounds were characterized by using elemental analysis, magnetic susceptibility measurements, conductivity, molar ratio, electronic, infrared, and NMR spectra, X-ray diffraction, and antioxidant analysis. The ligand was found to be a bidentate ligand involving the imino nitrogen and the nitrogen of amine in all complexes, in addition to the oxygen of the carbonyl group in NiΙΙ complex. The metal to ligand ratios were found to be 1:1 for all of the prepared complexes. The Co(II) and Ni(II) complexes have been found in a square planar geometry, while the complex of Cu(II) has octahedral geometry. Complexes of Co(II) and Ni(II) have electrolytic nature but the complex of Cu(II) was not. The ligand and its complexes were screened for their antifungal and antibacterial activity. The results indicated that these compounds exhibited good antifungal and antibacterial activities.

A new transition metal complexes of Cu (II), Co (II) , and Ni (II) were synthesized from the Schiff base (2-Furalidene-1-phenylsemicarbazide SB) and the organophosphorus Schiff base (2-Furalidenediphenylphosphate-1- phenylsemicarbazide OPSB). The ligands were characterized from their metal analysis, IR, UV-Vis, NMR, and XRD spectral studies. The structural features of complexes were obtained by their elemental analyses, magnetic susceptibility, molar conductance, IR, UV-Vis spectral, and molar ratio studies. The data showed that these complexes have the composition of ML2 for SB ligand and ML for OPSB. According to the UV-Vis, magnetic susceptibility data the octahedral geometry was suggested for all complexes. From XRD results, the practical size of ligands and SB complexes were in the nano range with crystallinity structure. The ligands and their metal complexes have been screened for their antioxidant, antibacterial and antifungal activity.

The objective of this manuscript is to study the possibility of improving the thermal performance of an Evacuated Tube Solar Collector with the integration of a Phase Change Material (PCM). A 2D mathematical model has been proposed. In addition, the feasibility of thermal coupling was studied. The objective of this study is to store all of the heat released during the absorption of hydrogen in a phase change material "Mg 69 Zn 28 Al 3 " For this, in this present study, we wanted to study the possibility of store the heat, released during hydrogen charging, in a phase change material (PCM), to restore it during the desorption step of the reactor The various results obtained will be presented and discussed.

Gallium nitride (GaN) films were grown on c-plane sapphire substrates treated with silicon nitride (SiN) by metalorganic chemical vapor deposition. Growth started with nitridation of the substrate of the sapphire, followed by treatment with SiN and then the growth was interrupted at the different stages of the film coalescence. For the different thicknesses, the GaN microstructure state was studied by High-resolution X-ray Diffraction measurements.  The a and c lattice constants were measured using symmetric and asymmetric ( /2θ) diffraction spectra. The in-plane and out-of-plane strains were determined and compared to fully relaxed GaN film . As the thickness of the GaN layer increases, the compressive room temperature strain increases and remain constant when the 2D growth mode is achieved.  Then, thermal, hydrostatic, and intrinsic stress levels have been determined for the different film coalescence levels. The growth of GaN layers is accompanied by intrinsic tensile stress generation which is reduced significantly with thickness and remains constant when the film reaches the 2D growth mode. The results demonstrate that all samples exhibit a lower isotopic hydrostatic compression deformation.  It is supposed that the hydrostatic strain in the epilayers is caused by native point defects. The type and concentration of the native defects suspected in the grown GaN thin films have been identified and estimated.

In This paper, we present the preparation of CdTe/CdS hetero structure thin films, in addition to study of the physical properties for the prepared thin films. The effect of changing the thickness on the structural properties and the lattice constants have been investigated. The change in the optical properties and the optical constants were also studied.

We have derived a new modified gravitational force that is an extension of Newton’s force of gravity. It shows that the observed velocity of stars inside galaxies (flat rotation curve) does not require dark matter. The new force produces logarithmic potential energy. This force is comparable to those of Gravitomagnetic force and Weber’s gravitational force. It is derived from Einstein’s general relativity by taking into consideration the velocity of a gravitating mass. This law treats the gravitational field as a fluid surround a gravitating mass in agreement of Maxwell assumption about the electromagnetic field. The fluid surrounding massive objects provide a background that acts like dark matter and dark energy partaking in cosmic expansion. Three modified laws of gravitation have been studied and are shown to give a velocity distribution profile in agreement with observations.

The present study reports the effect of the substrate temperature on the structural, morphological, and optical properties of ZnS semiconducting thin films grown via thermal evaporation technique. These properties have been thoroughly investigated using X-ray diffraction (XRD), atomic force microscopy (AFM), and UV-visible spectroscopy. The deposition was performed on a glass substrate at room temperature (RT), 100, 150, and 250°C. Energy dispersive spectrometry (EDS) analysis revealed a high purity of the ZnS films and non-stoichiometry atomic ration of Zn:S. The synthesized films exhibited cubic structure and developed on the (111) preferential orientation plane. Furthermore, increasing the substrate temperature improved the crystallinity and surface morphology of the thin films. Compared to others deposited films, the film grown at 250°C exhibited relatively high transparency in visible light (~87%), high absorption of the ultra violet (UV) light (~94 %.), and wide band gap (3.80 eV). Moreover, the refractive index was evaluated using Herve–Vandamme, Reddy, and Kumar and Singh models, and then compared. In general, these findings revealed that ZnS thin films can be used as the buffer layer in copper indium gallium selenide (CIGS) based solar cells.