Pyrazole Derivatives: A New Synthesis, Biological Importance, and Recent Practical Applications

Abstract

Heterocyclic compounds and their equivalents that include nitrogen have historically been valuable sources of pharmaceuticals. In a five-membered ring structure, the aromatic compound pyrazole, which contains two nitrogen atoms, offers a variety of uses and stereochemical complexity. Many pyrazole compounds have been shown to provide a variety of pharmacologic and physiological benefits in the last ten years of research. This is due to concerns that a substance's full potential may be limited by its drug-like qualities and how they relate to structure and activity. Different versions of the pyrazole nucleus allow for a wide range of uses in fields such as technology, medicine, and agriculture. They are specifically categorized as antioxidants, protein glycation inhibitors, antiviral, antibacterial, antifungal, anticancer, antidepressant, anti-inflammatory, and anti-tuberculosis. In this review, we proceed over the most significant findings made by scientists and chemists regarding the pyrazole compound, as well as general details and characteristics, different preparation techniques, its well-known derivatives, reactions, and biological uses, especially anti-bacterial, anti-microbial, anti-fungal, anti-malarial, and anti-cancer activity.